Does xyrem cause depression?
Even at recommended doses, Xyrem can cause confusion, depression, and other neuropsychiatric events. Important CNS adverse events caused by abuse of GHB include seizures, respiratory depression, and profound decreases in level of consciousness, sometimes leading to coma and death.
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Is Xyrem a depressant?
Xyrem (sodium oxybate) is a central nervous system depressant drug indicated for the treatment of excessive daytime sleepiness and cataplexy in patients with narcolepsy.
Can Xyrem cause anxiety?
It's possible to have anxiety while you're taking Xyrem. Symptoms of anxiety may include feeling nervous, panicking, or having an increased heart rate. Anxiety did occur in some people during Xyrem clinical trials, but it was a rare side effect.
Who should not take Xyrem?
It is not known if XYREM is safe and effective in children less than 7 years of age. Do not take XYREM if you or your child: takes other sleep medicines or sedatives (medicines that cause sleepiness) drinks alcohol.
What are the long term effects of Xyrem?
Respiratory Depression and Sleep-Disordered Breathing XYREM may impair respiratory drive, especially in patients with compromised respiratory function. In overdoses, life-threatening respiratory depression has been reported.
Can Xyrem cause psychosis?
Xyrem is usually well tolerated, but both psychosis and depression are described as possible adverse effects of this drug (6, 24–26).
Who should not take Xyrem?
It is not known if XYREM is safe and effective in children less than 7 years of age. Do not take XYREM if you or your child: takes other sleep medicines or sedatives (medicines that cause sleepiness) drinks alcohol.
What are the long term effects of Xyrem?
Respiratory Depression and Sleep-Disordered Breathing XYREM may impair respiratory drive, especially in patients with compromised respiratory function. In overdoses, life-threatening respiratory depression has been reported.
How many people died from Xyrem?
Fatalities resulting from popular use of gamma hydroxybutyrate (GHB) have previously been reported. We report three deaths associated with use of Xyrem (sodium oxybate), a pharmaceutical preparation of GHB initially approved for treatment of narcolepsy with cataplexy.
What kind of drug is Xyrem?
The prescription drug Xyrem is the sodium salt of gamma-hydroxybutyrate (GHB). GHB has not been approved for any medical use and has the potential for abuse, such as in cases of sexual assault. GHB is a Schedule I controlled substance under the Controlled Substances Act.
Can you drink alcohol on Xyrem?
You should not drink alcohol of any kind with XYREM. Why? Because the combination of XYREM with drinking alcohol can result in serious side effects, including trouble breathing or changes in alertness. Call your healthcare provider right away if you have any of these serious side effects.
Is sodium oxybate a depressant?
Sodium oxybate is a central nervous system depressant. It is also known as gamma hydroxybutyrate (GHB). This medication is used to treat narcolepsy, a condition that causes severe daytime sleepiness.
How long do I have to wait to take Xyrem after drinking alcohol?
You should wait at least 2 hours after eating before you take the first dose. Avoid alcohol during treatment, as it may add to the central nervous system effects of sodium oxybate and increase the risk of serious side effects such as respiratory depression, low blood pressure, fainting, coma, and even death.
Does Xyrem make you irritable?
In clinical trials in narcolepsy, a dose-response relationship was observed for nausea, vomiting, paresthesia, disorientation, irritability, disturbance in attention, feeling drunk, sleepwalking, and enuresis. The incidence of all these reactions was notably higher at 9 g per night.
Does Xyrem cause depression?
Even at recommended doses, Xyrem can cause confusion, depression, and other neuropsychiatric events. Important CNS adverse events caused by abuse of GHB include seizures, respiratory depression, and profound decreases in level of consciousness, sometimes leading to coma and death.
What are the long term effects of Xyrem?
Respiratory Depression and Sleep-Disordered Breathing XYREM may impair respiratory drive, especially in patients with compromised respiratory function. In overdoses, life-threatening respiratory depression has been reported.
Can Xyrem cause tachycardia?
Signs and symptoms of GHB withdrawal following abrupt discontinuation included insomnia, restlessness, anxiety, psychosis, lethargy, nausea, tremor, sweating, muscle cramps, tachycardia, headache, dizziness, rebound fatigue and sleepiness, confusion, and, particularly in the case of severe withdrawal, visual ...
How safe is Xyrem?
However, Xyrem, which is a form of GHB, is a Schedule Three (III) drug. This means that it does have an approved medical use. And it was shown to be safe and effective in treating narcolepsy during clinical studies.
What happens when you take Xyrem?
Xyrem can slow or stop your breathing, even at regular doses or if you are also taking stimulant medicines. Misuse of Xyrem can cause breathing problems, seizure, loss of consciousness, or death. Xyrem is available only from a certified pharmacy. Do not allow anyone else to use your medication.
Can you get high on Xyrem?
Xyrem has a high potential for abuse because it can cause changes in the activity of the brain and can also cause changes in your breathing, even at regular dosages or if you are taking other interacting medicines.
Does Xyrem make you sleep?
XYREM can cause sleep very quickly. Some people fall asleep within 5 minutes, and most people fall asleep within about 15 minutes. That is why you need to be in bed for each dose during the night.
What does Xyrem do to the body?
Xyrem is a central nervous system (CNS) depressant. This means that it works by relaxing your central nervous system. It affects your brain and certain nerves that control your muscles. This includes muscles that help you to breathe.
Does Xyrem cause weight gain?
Official Answer. Xyrem (sodium oxybate) can cause weight loss, which is thought to be due to the medication enabling people to increase their physical activity and decrease their calorie intake.
Does Xyrem cause depression?
Even at recommended doses, Xyrem can cause confusion, depression, and other neuropsychiatric events. Important CNS adverse events caused by abuse of GHB include seizures, respiratory depression, and profound decreases in level of consciousness, sometimes leading to coma and death.
Can you get high off Xyrem?
Xyrem has a high potential for abuse because it can cause changes in the activity of the brain and can also cause changes in your breathing, even at regular dosages or if you are taking other interacting medicines.